Associate Professor of Chemistry Adam Van Wynsberghe presented his research group’s work as part of the Syracuse University chemistry department’s seminar series on October 4. In “Development of a multi-scale sampling methodology to examine the favored ligand-binding pathways of influenza neuraminidase,” Van Wynsberghe discussed the recent efforts of the group to understand how small molecules bind to their protein targets.
The work of several Hamilton students and recent graduates was highlighted. In particular, research contributions by Erin Lewis ’18, Pat Marris ’16, Leah Krause ’14, Dan Mermelstein, ’14, Jeremy Adelman ’13 and Alvin Wu ’13 were broadly discussed. The research was conducted as part of summer research experiences, senior theses and independent studies.
The Van Wynsberghe research group uses computational and theoretical techniques to study protein-ligand binding and the functional implications of protein dynamics. The group’s general goals are to use chemical and physical principles to understand interesting problems in biochemistry and biophysics.